A chemical tank leak at an industrial facility in Toledo, Ohio, has forced evacuations and triggered a major emergency response after a ruptured tank released a potentially hazardous plume into the air.

The incident began Tuesday night at MC Tank Transport, prompting authorities to evacuate nearly 1,000 residents within an initial one-mile radius. More than 50,000 people were also advised to shelter indoors while officials assessed the risks.

The company said the tank contained glycidyl methacrylate, an industrial chemical used in manufacturing certain plastics, paints and coatings. Officials allowed the chemical to vent rather than risk sending emergency crews close to the unstable tank.

Residents reported eye and throat irritation, while a local healthcare provider evaluated around 30 people with possible symptoms. Authorities said monitoring and health assessments were continuing.

The leak also disrupted local activity, with schools closed and Stellantis temporarily halting production at its nearby Jeep assembly plant.

Officials reported that the plume was diminishing and the shelter-in-place order was lifted Wednesday evening, while the evacuation zone was reduced. Authorities continued assessing the site and potential health risks.

The incident highlights the challenges of industrial chemical emergencies and the importance of following official evacuation and public-safety instructions.